Sporozoite motility as a quantitative readout for anti-CSP antibody inhibition
Abstract Antibodies can prevent malaria by neutralizing the infectious Plasmodium falciparum sporozoites (SPZ) before they establish an infection in the liver.Circumsporozoite protein (CSP), the most abundant surface protein of Totes SPZ is the leading candidate for passive (and subunit) immunization approaches against malaria.Comprehensive assessm